Click to view the IRBs and Human Research Protection Program Organizational Chart.

The components of the HRPP within the Office of Research Compliance include:

Institutional Official

The Institutional Official (IO) is ultimately responsible for ensuring the protection of human participants at UW–Madison and maintaining oversight of the entire UW–Madison HRPP. There are two main components of the HRPP that provide administrative support and oversight of human participants research on campus: the IRBs/IRBs Office & the Office of Research Compliance.


Office of Research Compliance

The Office of Research Compliance (ORC) within the Office of the Vice Chancellor for Research oversees a range of HRPP administrative and compliance activities including reliance and navigation, post-approval monitoring, ClinicalTrials.gov registration and reporting, AAHRPP accreditation activities, and quality assurance oversight. The ORC supports key advisory committees to the IO including the Cross Campus HRPP Committee and the Quality and Compliance Oversight and Advisory Committee (QCOAC). Working groups to support the HRPP advisory committees and HRPP program include the Quality and Compliance Operations Committee (QCOC), the HRPP Policy Revision working group, the HRPP Education working group, the ClinicalTrials.gov committee, and the Post-Approval Monitoring working group.


Institutional Review Boards (IRBs)

The IRBs oversee research involving human participants conducted at UW-Madison. This includes research conducted off-site by University faculty and staff when acting as University employees or in connection with their University appointments. The IRBs review and oversee research to ensure that it meets ethical principles and complies with federal regulations, state laws, and university policies. The IRBs are composed of members from various disciplines in the medical, social, and behavioral sciences as well as community members. The IRBs are supported by the IRBs Office staff.


Reliance and Navigation Team (RELIANT)

The Reliance and Navigation Team (RELIANT) assists researchers with collaborative and multisite research issues and provides support to researchers in navigating institutional requirements.