Depending on the nature of your study, number of sites, and other factors, UW-Madison may not be your best option. This is not because the UW-Madison IRB does not want to support our researchers. Rather, we want to ensure the success for your study by helping identify the IRB which will meet the needs of your study. This assistance typically occurs through consultation with RELIANT.

Among the factors we will review with you:

• Number of study sites engaged in human research
• Timeframe for getting all study sites approved
  • If your study will have a narrow window in which to have all study sites approved, we will discuss with you how best to ensure your deadline is met
• Type of study sites
• Location of study sites and type of study interventions
  • If your study sites will be outside Wisconsin, additional considerations will apply in assessing your best reviewing IRB option, including whether:
    • Any state laws apply to your study and how IRB review must be conducted
    • Study interventions may require specific knowledge of local context to provide appropriate IRB review
    • Study sites have their own IRB/HRPP and, if not, what experience that site has with conducting human research, including qualified study personnel
• Budget considerations
  • While a commercial IRB may be the best option for your study, budgetary constraints may impact whether this is viable for your study.
    • Keep in mind that NIH will pay for sIRB review costs

For more information, see Appendix B- Single IRB Review Requirements.