The IRB will provide you with a written decision indicating that the IRB has approved the Human Research, requires modifications to secure approval, or has disapproved the Human Research.

• If the IRB has approved the human research:The human research may commence once all other institutional approvals have been met. IRB approval is usually good for a limited period of time which is noted in the approval letter. If no continuing review for your study is required, this also will be noted in the approval letter.
• If the IRB requires modifications to secure approval and you accept the modifications:Make the requested modifications and submit them to the IRB via ARROW. If all requested modifications are made, the IRB will issue a final approval. Research cannot commence until this final approval is received. If you do not accept the modifications, write up your response and submit it to the IRB.
• If the IRB defers the Human Research:The IRB will provide a statement of the reasons for deferral and suggestions to make the study approvable and give you an opportunity to respond in writing. In most cases if the IRB’s reasons for the deferral are addressed in a modification, the human research can be approved.
• If the IRB disapproves the human research:The IRB will provide a statement of the reasons for disapproval and give you an opportunity to respond in writing.

In all cases, you have the right to address your concerns to the IRB directly.