Unless the study qualifies for study closure at the time it expires, investigators must submit a continuing review application in order to secure a new approval period.

Research teams are responsible for monitoring when IRB approval of their studies expires, but will receive automated reminders from ARROW at 75, 60, and 30 days before a study expires.

To allow the IRB sufficient time to review and reapprove a study prior to the expiration date, please follow the required submission timelines for continuing reviews noted below.

  • For studies that were submitted and approved as initial reviews through ARROW, the continuing review protocol progress report needs to be provided to the IRB 45 days prior to the study’s expiration date.


We recommend reviewing the following documents from the HRPP Toolkit Library: