Since the launch of the HRPP Toolkit last March, we have been collecting feedback on the Toolkit materials from the research community, IRB staff, and HRPP leadership and making revisions every 6 months. The latest round of revisions went live the week of January 24, 2022. Updates to the Investigator Manual, Reliance Manual, and various templates were made. Additionally, updates were made to Toolkit checklists and worksheets that IRB Staff have been using to conduct reviews for the past several months. As a reminder, we welcome feedback via the Toolkit Feedback Form or by email (